Tag Archives: and-receive

Alcohol in the News

(Source: About.com Alcoholism) MedWorm Message: Register for MedMatcha, MedWorm's medical advertising network , and receive $5 free advertising.
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Acupuncture Inhibits GABA Neuron Activity in the Ventral Tegmental Area and Reduces Ethanol Self-Administration.

Conclusions:  These findings suggest that DOR-mediated opioid modulation of VTA GABA neurons may mediate acupuncture's role in modulating mesolimbic DA release and suppressing the reinforcing effects of ethanol. PMID: 20860620 [PubMed - as supplied by publisher] (Source: Alcoholism, Clinical and Experimental Research) MedWorm Message: Register for MedMatcha, MedWorm's medical advertising network , and receive $5 free advertising.
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Behavioral Effects of Ethanol in Cerebellum Are Age Dependent: Potential System and Molecular Mechanisms.

Conclusions:  Adolescents are less sensitive than adults to the motor-impairing effects of ethanol, and a similar effect is seen with in vivo electrophysiological recordings of cerebellar Purkinje neurons. While still under investigation, PKCγ expression mirrors the age effect of ethanol and may contribute to the age-dependent differences in the ataxic effects of ethanol
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Target-specific, histology-independent, randomized discontinuation study of lapatinib in patients with HER2-amplified solid tumors

Conclusions: Basing trial eligibility on the presence of a genetic target, versus histologic classification, is challenging. While HER2 amplifications appear to be prevalent in select non-breast tumors, lapatinib monotherapy is associated with modest activity.
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Prenatal methadone exposure, meconium biomarker concentrations and neonatal abstinence syndrome

ABSTRACT (Source: Addiction) MedWorm Message: Register for MedMatcha, MedWorm's medical advertising network , and receive $5 free advertising.
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Experimental effect of positive urgency on negative outcomes from risk taking and on increased alcohol consumption.

The current pair of experimental studies sought to further validate the role of positive urgency (acting rashly when in an extreme positive emotional state) as a risk factor for impulsive and maladaptive behavior. Previous research has supported the use of emotion-based dispositions to rash action in predicting a wide range of maladaptive acts. However, that research was conducted in the field and relied on self-reported behavior, thus lacking tight experimental controls and direct observation of risky behaviors.
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Prescription drug misuse among dating partners: Within-couple associations and implications for intimate relationship quality.

This study examined the associations between dating partners' misuse of prescription medications and the implications of misuse for intimate relationship quality. A sample of 100 young adult dating pairs completed ratings of prescription drug use and misuse, alcohol use, and relationship quality
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Clinical outcomes of an integrated treatment for depression and substance use disorders.

The authors compared longitudinal treatment outcomes for depressed substance-dependent veterans (N = 206) assigned to integrated cognitive–behavioral therapy plus standard pharmacotherapy (ICBT + P) or 12-step facilitation therapy plus standard pharmacotherapy (TSF + P). Drug and alcohol involvement and depressive symptomology were measured at intake and at 3-month intervals during treatment and up to 1 year posttreatment. Participants in both treatment conditions showed decreased depression and substance use from intake.
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Electrophysiological evidence of alcohol-related attentional bias in social drinkers low in alcohol sensitivity.

Low sensitivity to the acute effects of alcohol is a known risk factor for alcoholism. However, little is known concerning potential information-processing routes by which this risk factor might contribute to increased drinking. We tested the hypothesis that low-sensitivity (LS) participants would show biased attention to alcohol cues, compared with their high-sensitivity (HS) counterparts.
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Motor vehicle collision fatalities involving alcohol and illicit drugs in Greece: the need for management protocols and a reassessment of surveillance

ABSTRACT (Source: Addiction) MedWorm Message: Register for MedMatcha, MedWorm's medical advertising network , and receive $5 free advertising.
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